Difference between revisions of "AroD"

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Revision as of 13:58, 16 May 2013

  • Description: shikimate dehydrogenase

Gene name aroD
Synonyms
Essential no
Product shikimate dehydrogenase
Function biosynthesis of aromatic amino acids
Gene expression levels in SubtiExpress: aroD
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 30 kDa, 6.077
Gene length, protein length 840 bp, 280 aa
Immediate neighbours yqeI, yqeH
Sequences Protein DNA DNA_with_flanks
Genetic context
AroD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AroD expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25660

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Shikimate + NADP+ = 3-dehydroshikimate + NADPH (according to Swiss-Prot)
  • Protein family: shikimate dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2HK8 (from Aquifex aeolicus, 42% identity, 61% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References