Difference between revisions of "PurR"
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=purR_54441_55298_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:purR_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=purR_54441_55298_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:purR_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00470]] |
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Revision as of 12:18, 16 May 2013
- Description: transcription repressor of the pur operon
| Gene name | purR |
| Synonyms | yabI |
| Essential | no |
| Product | transcription repressor of the pur operon |
| Function | regulation of purine biosynthesis |
| Gene expression levels in SubtiExpress: purR | |
| Interactions involving this protein in SubtInteract: PurR | |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation), Ala, Gly, Ser | |
| MW, pI | 31 kDa, 5.771 |
| Gene length, protein length | 855 bp, 285 aa |
| Immediate neighbours | ispE, yabJ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, transcription factors and their control
This gene is a member of the following regulons
The PurR regulon
The gene
Basic information
- Locus tag: BSU00470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Biological activity: transcriptional repressor of purine biosynthetic operons
- Protein family: purine/pyrimidine phosphoribosyltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: PRPP acts as inducer, binding results in release of PurR from the operator PubMed
Database entries
- UniProt: P37551
- KEGG entry: [3]
- E.C. number:
Additional information
requires YabJ for in vivo activity
Expression and regulation
- Sigma factor:
- Regulation: negative autoregulation, induction in the presence of PRPP PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
