Difference between revisions of "RpsD"
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytrP]]'', ''[[tyrS]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytrP]]'', ''[[tyrS]]'' | ||
|- | |- | ||
− | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29660 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29660 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29660 | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29660 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29660 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29660 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:rpsD_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:rpsD_context.gif]] |
Revision as of 11:01, 14 May 2013
- Description: ribosomal protein
Gene name | rpsD |
Synonyms | |
Essential | yes PubMed |
Product | ribosomal protein S4 (BS4) |
Function | translation |
Gene expression levels in SubtiExpress: rpsD | |
Interactions involving this protein in SubtInteract: RpsD | |
MW, pI | 22 kDa, 10.243 |
Gene length, protein length | 600 bp, 200 aa |
Immediate neighbours | ytrP, tyrS |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
translation, essential genes, universally conserved proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29660
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ribosomal protein S4P family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1C06 (Geobacillus stearothermophilus)
- UniProt: P21466
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- RelA dependent downregulation (Class I) during stringent response PubMed
- autorepression of rpsD expression upon binding of excess RpsD to a RNA switch in the untranslated region of the rpsD mRNA PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kaila Deiorio-Haggar, Jon Anthony, Michelle M Meyer
RNA structures regulating ribosomal protein biosynthesis in bacilli.
RNA Biol: 2013, 10(7);1180-4
[PubMed:23611891]
[WorldCat.org]
[DOI]
(I p)
Genki Akanuma, Hideaki Nanamiya, Yousuke Natori, Koichi Yano, Shota Suzuki, Shuya Omata, Morio Ishizuka, Yasuhiko Sekine, Fujio Kawamura
Inactivation of ribosomal protein genes in Bacillus subtilis reveals importance of each ribosomal protein for cell proliferation and cell differentiation.
J Bacteriol: 2012, 194(22);6282-91
[PubMed:23002217]
[WorldCat.org]
[DOI]
(I p)
Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700]
[WorldCat.org]
[DOI]
(P p)
T Inaoka, K Kasai, K Ochi
Construction of an in vivo nonsense readthrough assay system and functional analysis of ribosomal proteins S12, S4, and S5 in Bacillus subtilis.
J Bacteriol: 2001, 183(17);4958-63
[PubMed:11489846]
[WorldCat.org]
[DOI]
(P p)
F J Grundy, T M Henkin
Characterization of the Bacillus subtilis rpsD regulatory target site.
J Bacteriol: 1992, 174(21);6763-70
[PubMed:1400226]
[WorldCat.org]
[DOI]
(P p)
F J Grundy, T M Henkin
The rpsD gene, encoding ribosomal protein S4, is autogenously regulated in Bacillus subtilis.
J Bacteriol: 1991, 173(15);4595-602
[PubMed:1906866]
[WorldCat.org]
[DOI]
(P p)
T M Henkin, G H Chambliss, F J Grundy
Bacillus subtilis mutants with alterations in ribosomal protein S4.
J Bacteriol: 1990, 172(11);6380-5
[PubMed:2121712]
[WorldCat.org]
[DOI]
(P p)
F J Grundy, T M Henkin
Cloning and analysis of the Bacillus subtilis rpsD gene, encoding ribosomal protein S4.
J Bacteriol: 1990, 172(11);6372-9
[PubMed:1699930]
[WorldCat.org]
[DOI]
(P p)
T M Henkin, G H Chambliss
Genetic mapping of a mutation causing an alteration in Bacillus subtilis ribosomal protein S4.
Mol Gen Genet: 1984, 193(2);364-9
[PubMed:6420647]
[WorldCat.org]
[DOI]
(P p)