DppA

• Description: D-alanyl-aminopeptidase
  
  

Gene name	dppA
Synonyms	dciAA
Essential	no
Product	D-alanyl-aminopeptidase
Function	degradation of cell wall peptides
Gene expression levels in SubtiExpress: dppA
Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources
MW, pI	30 kDa, 5.19
Gene length, protein length	822 bp, 274 aa
Immediate neighbours	proG, dppB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, phosphoproteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

• Locus tag: BSU12920

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M55 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on ser/ thr/ tyr PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1HI9

• UniProt: P26902

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dppA-dppB-dppC-dppD-dppE PubMed

• Expression browser: dppA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (2.9-fold) PubMed
  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed

• Regulatory mechanism:
  • CodY: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: