Difference between revisions of "DltA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichoic acid | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichoic acid | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38500 dltA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 55 kDa, 4.929 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 55 kDa, 4.929 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywzH]]'', ''[[dltB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywzH]]'', ''[[dltB]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38500 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38500 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38500 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:dltA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:dltA_context.gif]] | ||
Revision as of 14:11, 13 May 2013
- Description: D-alanyl-D-alanine carrier protein ligase, alanylation of teichoic acid provides some resistance against positively charged antimicrobial peptides
| Gene name | dltA |
| Synonyms | ipa-5r, dae |
| Essential | no |
| Product | D-alanyl-D-alanine carrier protein ligase |
| Function | biosynthesis of teichoic acid |
| Gene expression levels in SubtiExpress: dltA | |
| MW, pI | 55 kDa, 4.929 |
| Gene length, protein length | 1509 bp, 503 aa |
| Immediate neighbours | ywzH, dltB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
SigD regulon, SigM regulon, SigX regulon, Spo0A regulon, stringent response, YvrHb regulon
The gene
Basic information
- Locus tag: BSU38500
Phenotypes of a mutant
- increased sensitivity to lysozyme PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate) (according to Swiss-Prot)
- Protein family: DltA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 3E7X
- UniProt: P39581
- KEGG entry: [3]
- E.C. number: 6.1.1.13
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
Additional publications: PubMed
