Difference between revisions of "QoxA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || respiration  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || respiration  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU38170 qoxA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38170 qoxA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 4.796   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 4.796   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[qoxB]]'', ''[[ywzA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[qoxB]]'', ''[[ywzA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15843&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38170 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38170 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38170 Advanced_DNA]
 
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Revision as of 14:10, 13 May 2013

  • Description: cytochrome aa3 quinol oxidase (subunit II)

Gene name qoxA
Synonyms ipa-37d
Essential no
Product cytochrome aa3 quinol oxidase (subunit II)
Function respiration
Gene expression levels in SubtiExpress: qoxA
MW, pI 36 kDa, 4.796
Gene length, protein length 963 bp, 321 aa
Immediate neighbours qoxB, ywzA
Sequences Protein DNA Advanced_DNA
Genetic context
QoxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
QoxA expression.png















Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU38170

Phenotypes of a mutant

  • inactivation of qoxA restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O (according to Swiss-Prot)
  • Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed