Difference between revisions of "RodA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of cell shape and elongation | |style="background:#ABCDEF;" align="center"|'''Function''' || control of cell shape and elongation | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38120 rodA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 8.759 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 8.759 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nfrA]]'', ''[[ywcE]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nfrA]]'', ''[[ywcE]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38120 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38120 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38120 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:rodA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:rodA_context.gif]] | ||
Revision as of 14:10, 13 May 2013
- Description: control of cell shape and elongation
| Gene name | rodA |
| Synonyms | ywcF, ipa-42d |
| Essential | yes PubMed |
| Product | SEDS protein |
| Function | control of cell shape and elongation |
| Gene expression levels in SubtiExpress: rodA | |
| MW, pI | 43 kDa, 8.759 |
| Gene length, protein length | 1179 bp, 393 aa |
| Immediate neighbours | nfrA, ywcE |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell shape, cell envelope stress proteins (controlled by SigM, V, W, X, Y), essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38120
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- part of the cell wall biosynthetic complex PubMed
Database entries
- Structure:
- UniProt: P39604
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rodA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745]
[WorldCat.org]
[DOI]
(I p)
Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744]
[WorldCat.org]
[DOI]
(I p)
Gonçalo Real, Allison Fay, Avigdor Eldar, Sérgio M Pinto, Adriano O Henriques, Jonathan Dworkin
Determinants for the subcellular localization and function of a nonessential SEDS protein.
J Bacteriol: 2008, 190(1);363-76
[PubMed:17981970]
[WorldCat.org]
[DOI]
(I p)
A O Henriques, P Glaser, P J Piggot, C P Moran
Control of cell shape and elongation by the rodA gene in Bacillus subtilis.
Mol Microbiol: 1998, 28(2);235-47
[PubMed:9622350]
[WorldCat.org]
[DOI]
(P p)
