Difference between revisions of "Mta"

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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of multidrug-efflux transporter genes
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of multidrug-efflux transporter genes
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU36600 mta]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36600 mta]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.949   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.949   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[clsA]]'', ''[[ywnC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[clsA]]'', ''[[ywnC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15677&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36600 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36600 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36600 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:mta_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:mta_context.gif]]

Revision as of 14:04, 13 May 2013

  • Description: transcriptional activator of multidrug-efflux transporter genes, activates ymfD expression

Gene name mta
Synonyms ywnD
Essential no
Product transcriptional activator
Function regulation of multidrug-efflux transporter genes
Gene expression levels in SubtiExpress: mta
MW, pI 29 kDa, 4.949
Gene length, protein length 771 bp, 257 aa
Immediate neighbours clsA, ywnC
Sequences Protein DNA Advanced_DNA
Genetic context
Mta context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Mta expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics

This gene is a member of the following regulons

Mta regulon

The Mta regulon

The gene

Basic information

  • Locus tag: BSU36600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1JBG (N-terminal domain), 1R8D (complex of N-terminal domain with DNA)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • positive autoregulation PubMed
  • Regulatory mechanism:
    • Mta: transcription activation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Richard Brennan, Houston, Texas, USA Homepage

Your additional remarks

References