Difference between revisions of "CopA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || copper export, detoxification | |style="background:#ABCDEF;" align="center"|'''Function''' || copper export, detoxification | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33500 copA] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/CopA CopA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/CopA CopA] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cadA]]'', ''[[copZ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cadA]]'', ''[[copZ]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33500 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33500 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33500 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:yvgX_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yvgX_context.gif]] | ||
Revision as of 13:50, 13 May 2013
- Description: copper-transporting ATPase, resistance to copper
| Gene name | copA |
| Synonyms | yvgX |
| Essential | no |
| Product | copper transporting ATPase |
| Function | copper export, detoxification |
| Gene expression levels in SubtiExpress: copA | |
| Interactions involving this protein in SubtInteract: CopA | |
| Metabolic function and regulation of this protein in SubtiPathways: metal ion homeostasis | |
| MW, pI | 85 kDa, 5.484 |
| Gene length, protein length | 2409 bp, 803 aa |
| Immediate neighbours | cadA, copZ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), resistance against toxic metals, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU33500
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + H2O + Cu1+(In) = ADP + phosphate + Cu1+(Out) (according to Swiss-Prot)
- Protein family: Type IB subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- two N-terminal soluble domains, CopAa and CopAb, connected by a short linker
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 2RML ( N-terminal soluble domain)
- UniProt: O32220
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
Reviews
Original publications
Additional publications: PubMed
