Difference between revisions of "HemB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28130 hemB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 4.98 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 4.98 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hemL]]'', ''[[hemD]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hemL]]'', ''[[hemD]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28130 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28130 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28130 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:hemB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:hemB_context.gif]] | ||
Revision as of 13:29, 13 May 2013
- Description: porphobilinogen synthase
| Gene name | hemB |
| Synonyms | |
| Essential | no |
| Product | porphobilinogen synthase |
| Function | heme biosynthesis |
| Gene expression levels in SubtiExpress: hemB | |
| MW, pI | 36 kDa, 4.98 |
| Gene length, protein length | 972 bp, 324 aa |
| Immediate neighbours | hemL, hemD |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28130
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2 5-aminolevulinate = porphobilinogen + 2 H2O (according to Swiss-Prot)
- Protein family: ALADH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-217 PubMed
- Cofactor(s): zinc
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P30950
- KEGG entry: [3]
- E.C. number: 4.2.1.24
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
