Difference between revisions of "Rnz"
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|style="background:#ABCDEF;" align="center"|'''Function''' || processing of CCA-less tRNA precursors | |style="background:#ABCDEF;" align="center"|'''Function''' || processing of CCA-less tRNA precursors | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23840 rnz] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.805 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.805 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqjL]]'', ''[[zwf]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqjL]]'', ''[[zwf]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23840 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23840 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23840 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yqjK_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yqjK_context.gif]] | ||
Revision as of 13:13, 13 May 2013
- Description: RNase Z
| Gene name | rnz |
| Synonyms | yqjK |
| Essential | yes PubMed |
| Product | endoribonuclease Z |
| Function | processing of CCA-less tRNA precursors |
| Gene expression levels in SubtiExpress: rnz | |
| MW, pI | 33 kDa, 5.805 |
| Gene length, protein length | 921 bp, 307 aa |
| Immediate neighbours | yqjL, zwf |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
Rnases, translation, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23840
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs (according to Swiss-Prot)
- Protein family: RNase Z family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P54548
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rnz (according to DBTBS)
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Ciaran Condon, IBPC, Paris, France Homepage
Your additional remarks
References
Reviews
Roland K Hartmann, Markus Gössringer, Bettina Späth, Susan Fischer, Anita Marchfelder
The making of tRNAs and more - RNase P and tRNase Z.
Prog Mol Biol Transl Sci: 2009, 85;319-68
[PubMed:19215776]
[WorldCat.org]
[DOI]
(P p)
B Späth, G Canino, A Marchfelder
tRNase Z: the end is not in sight.
Cell Mol Life Sci: 2007, 64(18);2404-12
[PubMed:17599240]
[WorldCat.org]
[DOI]
(P p)
Original Publications
