Difference between revisions of "YonN"

From SubtiWiki
Jump to: navigation, search
Line 14: Line 14:
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU21050 yonN]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21050 yonN]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 10.227   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 10.227   
Line 22: Line 22:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yonO]]'', ''[[yonK]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yonO]]'', ''[[yonK]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14023&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU21050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU21050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU21050 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yonN_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yonN_context.gif]]

Revision as of 13:04, 13 May 2013

  • Description: similar to HU-related DNA-binding protein

Gene name yonN
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yonN
MW, pI 9 kDa, 10.227
Gene length, protein length 276 bp, 92 aa
Immediate neighbours yonO, yonK
Sequences Protein DNA Advanced_DNA
Genetic context
YonN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YonN expression.png















Categories containing this gene/protein

genetics/ other, SP-beta prophage

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • YonN-mediated untwisting of the DNA stimulates Nth endonuclease activity at AP sites PubMed
  • Protein family: glycosyltransferase 1 family (according to Swiss-Prot)
  • Paralogous protein(s): Hbs

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Christopher Collier, Cristina Machón, Geoff S Briggs, Wiep Klaas Smits, Panos Soultanas
Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites.
Nucleic Acids Res: 2012, 40(2);739-50
[PubMed:21954439] [WorldCat.org] [DOI] (I p)