Difference between revisions of "ParE"
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|style="background:#ABCDEF;" align="center"|'''Function''' || chromosome segregation and compaction | |style="background:#ABCDEF;" align="center"|'''Function''' || chromosome segregation and compaction | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18090 parE] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 72 kDa, 6.166 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 72 kDa, 6.166 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yneT]]'', ''[[parC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yneT]]'', ''[[parC]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18090 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18090 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18090 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:parE_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:parE_context.gif]] | ||
Revision as of 12:57, 13 May 2013
- Description: subunit of DNA topoisomerase IV
| Gene name | parE |
| Synonyms | grlB |
| Essential | yes PubMed |
| Product | subunit of DNA topoisomerase IV |
| Function | chromosome segregation and compaction |
| Gene expression levels in SubtiExpress: parE | |
| MW, pI | 72 kDa, 6.166 |
| Gene length, protein length | 1965 bp, 655 aa |
| Immediate neighbours | yneT, parC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
DNA condensation/ segregation, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU18090
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: type II topoisomerase family (according to Swiss-Prot)
- Paralogous protein(s): GyrB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q59192
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537]
[WorldCat.org]
[DOI]
(P p)
Serkalem Tadesse, Judita Mascarenhas, Bernd Kösters, Andrej Hasilik, Peter L Graumann
Genetic interaction of the SMC complex with topoisomerase IV in Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 11);3729-3737
[PubMed:16272394]
[WorldCat.org]
[DOI]
(P p)
Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290]
[WorldCat.org]
[DOI]
(P p)
W M Huang, J L Libbey, P van der Hoeven, S X Yu
Bipolar localization of Bacillus subtilis topoisomerase IV, an enzyme required for chromosome segregation.
Proc Natl Acad Sci U S A: 1998, 95(8);4652-7
[PubMed:9539793]
[WorldCat.org]
[DOI]
(P p)
