Difference between revisions of "YneA"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || inhibits cell division during SOS response | |style="background:#ABCDEF;" align="center"|'''Function''' || inhibits cell division during SOS response | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17860 yneA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 4.613 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 4.613 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lexA]]'', ''[[yneB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lexA]]'', ''[[yneB]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17860 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17860 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17860 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yneA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yneA_context.gif]] | ||
Revision as of 12:56, 13 May 2013
- Description: inhibits cell division during SOS response
| Gene name | yneA |
| Synonyms | |
| Essential | no |
| Product | cell division control protein |
| Function | inhibits cell division during SOS response |
| Gene expression levels in SubtiExpress: yneA | |
| MW, pI | 11 kDa, 4.613 |
| Gene length, protein length | 315 bp, 105 aa |
| Immediate neighbours | lexA, yneB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU17860
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: yneA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- LysM peptidoglycan binding domain PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted to the medium (signal peptide) PubMed
Database entries
- Structure:
- UniProt: Q45056
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
- YneA is rapidly degraded by extracellular proteases PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Allison H Mo, William F Burkholder
YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.
J Bacteriol: 2010, 192(12);3159-73
[PubMed:20400548]
[WorldCat.org]
[DOI]
(I p)
Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290]
[WorldCat.org]
[DOI]
(P p)
Yoshikazu Kawai, Shigeki Moriya, Naotake Ogasawara
Identification of a protein, YneA, responsible for cell division suppression during the SOS response in Bacillus subtilis.
Mol Microbiol: 2003, 47(4);1113-22
[PubMed:12581363]
[WorldCat.org]
[DOI]
(P p)
