Difference between revisions of "QueE"
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|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification | |style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13740 queE] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 4.962 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 4.962 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[queD]]'', ''[[queF]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[queD]]'', ''[[queF]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13740 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykvL_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ykvL_context.gif]] | ||
Revision as of 12:40, 13 May 2013
- Description: 7-carboxy-7-deazaguanine (CDG) synthase, required for the synthesis of the modified ribonucleotide queuosine
| Gene name | queE |
| Synonyms | ykvL |
| Essential | no |
| Product | 7-carboxy-7-deazaguanine (CDG) synthase |
| Function | tRNA modification |
| Gene expression levels in SubtiExpress: queE | |
| MW, pI | 26 kDa, 4.962 |
| Gene length, protein length | 729 bp, 243 aa |
| Immediate neighbours | queD, queF |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13740
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- conversion of 6-carboxy-5,6,7,8-tetrahydropterin to 7-carboxy-7-deazaguanine (CDG) PubMed
- Catalyzed reaction/ biological activity:
- Protein family: radical S-adenosyl-L-methionine (SAM) superfamily
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): [4Fe-4S] cluster, S-adenosyl-L-methionine, Mg(2+) PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31677
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- repressed in the presence of queuosine (preQ1 riboswitch) PubMed
- Regulatory mechanism:
- preQ1 riboswitch: transcriptional antitermination in the absence of queuosine PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
