Difference between revisions of "TlpC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || control of chemotaxis  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of chemotaxis  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03440 tlpC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03440 tlpC]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 61 kDa, 4.929   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 61 kDa, 4.929   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nucA]]'', ''[[hxlB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nucA]]'', ''[[hxlB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12138&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03440 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03440 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03440 Advanced_DNA]
 
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Revision as of 12:07, 13 May 2013

  • Description: membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein

Gene name tlpC
Synonyms
Essential no
Product methyl-accepting chemotaxis protein
Function control of chemotaxis
Gene expression levels in SubtiExpress: tlpC
MW, pI 61 kDa, 4.929
Gene length, protein length 1719 bp, 573 aa
Immediate neighbours nucA, hxlB
Sequences Protein DNA Advanced_DNA
Genetic context
TlpC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TlpC expression.png


























Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU03440

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • in minimal medium,TlpC is present with 5,400 +/- 1700 molecules per cell PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Vincent J Cannistraro, George D Glekas, Christopher V Rao, George W Ordal
Cellular stoichiometry of the chemotaxis proteins in Bacillus subtilis.
J Bacteriol: 2011, 193(13);3220-7
[PubMed:21515776] [WorldCat.org] [DOI] (I p)

D van Sinderen, R Kiewiet, G Venema
Differential expression of two closely related deoxyribonuclease genes, nucA and nucB, in Bacillus subtilis.
Mol Microbiol: 1995, 15(2);213-23
[PubMed:7746143] [WorldCat.org] [DOI] (P p)

D W Hanlon, M M Rosario, G W Ordal, G Venema, D Van Sinderen
Identification of TlpC, a novel 62 kDa MCP-like protein from Bacillus subtilis.
Microbiology (Reading): 1994, 140 ( Pt 8);1847-54
[PubMed:7921238] [WorldCat.org] [DOI] (P p)