Difference between revisions of "GlpQ"
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|style="background:#ABCDEF;" align="center"|'''Function''' || glycerol-3-phosphate utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || glycerol-3-phosphate utilization | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02130 glpQ] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 9.263 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 9.263 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybeC]]'', ''[[glpT]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybeC]]'', ''[[glpT]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02130 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02130 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02130 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:glpQ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:glpQ_context.gif]] | ||
Revision as of 12:02, 13 May 2013
- Description: glycerolphosphate diester phosphodiesterase
| Gene name | glpQ |
| Synonyms | ybeD |
| Essential | no |
| Product | glycerolphosphate diester phosphodiesterase |
| Function | glycerol-3-phosphate utilization |
| Gene expression levels in SubtiExpress: glpQ | |
| MW, pI | 32 kDa, 9.263 |
| Gene length, protein length | 879 bp, 293 aa |
| Immediate neighbours | ybeC, glpT |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of specific carbon sources, utilization of lipids
This gene is a member of the following regulons
CcpA regulon, GlpP regulon, PhoP regulon
The gene
Basic information
- Locus tag: BSU02130
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate (according to Swiss-Prot)
- Protein family: glycerophosphoryl diester phosphodiesterase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- extracellular (signal peptide) PubMed
Database entries
- UniProt: P37965
- KEGG entry: [3]
- E.C. number: 3.1.4.46
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- CcpA: transcription repression
- GlpP: transcriptional antitermination via a protein-dependent RNA switch
- PhoP: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862]
[WorldCat.org]
[DOI]
(I p)
Liang Shi, Jun-Feng Liu, Xiao-Min An, Dong-Cai Liang
Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: insight into the catalytic mechanism.
Proteins: 2008, 72(1);280-8
[PubMed:18214974]
[WorldCat.org]
[DOI]
(I p)
H Antelmann, C Scharf, M Hecker
Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis.
J Bacteriol: 2000, 182(16);4478-90
[PubMed:10913081]
[WorldCat.org]
[DOI]
(P p)
R P Nilsson, L Beijer, B Rutberg
The glpT and glpQ genes of the glycerol regulon in Bacillus subtilis.
Microbiology (Reading): 1994, 140 ( Pt 4);723-30
[PubMed:8012593]
[WorldCat.org]
[DOI]
(P p)
