YvaK

• Description: general stress protein, similar to carboxylesterase
  
  

Gene name	yvaK
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yvaK
MW, pI	28 kDa, 4.992
Gene length, protein length	744 bp, 248 aa
Immediate neighbours	rnr, secG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU33620

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: A carboxylic ester + H₂O = an alcohol + a carboxylate (according to Swiss-Prot)

• Protein family: lipase/esterase LIP3/bchO family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1TQH (Geobacillus stearothermophilus)

• UniProt: O32232

• KEGG entry: [2]

• E.C. number: 3.1.1.1

Expression and regulation

• Operon:
  • secG-yvaK-rnr-smpB-ssrA PubMed
  • yvaK-rnr-smpB-ssrA PubMed

• Expression browser: yvaK PubMed

• Sigma factor:
  • yvaK: SigB PubMed

• Regulation:
  • yvaK: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ji-Hyun Shin, Chester W Price
The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.
J Bacteriol: 2007, 189(10);3729-37
[PubMed:17369301] [WorldCat.org] [DOI] (P p)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)