Difference between revisions of "NtdB"
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| − | * '''Description:''' | + | * '''Description:''' kanosamine-6-phosphate phosphatase <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || kanosamine-6-phosphate phosphatase |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic | + | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic kanosamine |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10540 ntdB] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10540 ntdB] | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** kanosamine-6-phosphate --> kanosamine {{PubMed|23586652}} | ||
* '''Protein family:''' Cof family (according to Swiss-Prot) | * '''Protein family:''' Cof family (according to Swiss-Prot) | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ntdB_1127466_1128314_-1 ntdB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ntdB_1127466_1128314_-1 ntdB] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|14612444}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|14612444}} |
* '''Regulation:''' induced by 3,3'-neotrehalosadiamine ([[NtdR]]) {{PubMed|14612444}} | * '''Regulation:''' induced by 3,3'-neotrehalosadiamine ([[NtdR]]) {{PubMed|14612444}} | ||
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<pubmed> 21512256</pubmed> | <pubmed> 21512256</pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>19087206,17056753 ,14612444 </pubmed> | + | <pubmed>19087206,17056753 ,14612444 23586652 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:37, 19 April 2013
- Description: kanosamine-6-phosphate phosphatase
| Gene name | ntdB |
| Synonyms | yhjK |
| Essential | no |
| Product | kanosamine-6-phosphate phosphatase |
| Function | synthesis of the antibiotic kanosamine |
| Gene expression levels in SubtiExpress: ntdB | |
| MW, pI | 33 kDa, 5.352 |
| Gene length, protein length | 858 bp, 286 aa |
| Immediate neighbours | ntdC, ntdA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10540
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- kanosamine-6-phosphate --> kanosamine PubMed
- Protein family: Cof family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3GYG
- UniProt: O07565
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256]
[WorldCat.org]
[DOI]
(I p)
Original publications
