Difference between revisions of "RsbS"
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| − | + | scaffold protein of the [[stressosome]], anti-[[RsbT]] | |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || anti-[[RsbT]] | + | |style="background:#ABCDEF;" align="center"| '''Product''' || scaffold protein of the [[stressosome]], anti-[[RsbT]] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Domains:''' | * '''Domains:''' | ||
| − | * '''Modification:''' phosphorylation on Ser-59 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed], dephosphorylation by [[RsbX]] {{PubMed|21362065}} | + | * '''Modification:''' phosphorylation on Ser-59 by [[RsbT]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed], dephosphorylation by [[RsbX]] {{PubMed|21362065}} |
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsbS_520237_520602_1 rsbS] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsbS_520237_520602_1 rsbS] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | + | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] |
* '''Regulation:''' constitutively expressed {{PubMed|20019076}} | * '''Regulation:''' constitutively expressed {{PubMed|20019076}} | ||
| Line 154: | Line 150: | ||
==Original Articles== | ==Original Articles== | ||
| − | '''Additional publications:''' {{PubMed|21362065}} | + | '''Additional publications:''' {{PubMed|23320651,21362065}} |
<pubmed>8002610,8682769,9786195,8682789,10781545, 15583165,8824586,10329124,17158665, 21821766 16321960,10671474,8808936,15312768,11244072,15342582,,16321960, 8955331, 12950928, 15466036, 9179850, 18832644 ,17218307 20019076</pubmed> | <pubmed>8002610,8682769,9786195,8682789,10781545, 15583165,8824586,10329124,17158665, 21821766 16321960,10671474,8808936,15312768,11244072,15342582,,16321960, 8955331, 12950928, 15466036, 9179850, 18832644 ,17218307 20019076</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:19, 5 February 2013
scaffold protein of the stressosome, anti-RsbT
| Gene name | rsbS |
| Synonyms | ycxS |
| Essential | no |
| Product | scaffold protein of the stressosome, anti-RsbT |
| Function | control of SigB activity |
| Gene expression levels in SubtiExpress: rsbS | |
| Interactions involving this protein in SubtInteract: RsbS | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 13 kDa, 4.14 |
| Gene length, protein length | 363 bp, 121 aa |
| Immediate neighbours | rsbR, rsbT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
sigma factors and their control, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3VY9 (complete stressosome)
- UniProt: P42410
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
- Rick Lewis, Newcastle, UK homepage
Your additional remarks
References
Reviews
Jon Marles-Wright, Richard J Lewis
The stressosome: molecular architecture of a signalling hub.
Biochem Soc Trans: 2010, 38(4);928-33
[PubMed:20658979]
[WorldCat.org]
[DOI]
(I p)
Jon Marles-Wright, Richard J Lewis
The Bacillus subtilis stressosome: A signal integration and transduction hub.
Commun Integr Biol: 2008, 1(2);182-4
[PubMed:19704888]
[WorldCat.org]
[DOI]
(I p)
Jan Pané-Farré, Richard J Lewis, Jörg Stülke
The RsbRST stress module in bacteria: a signalling system that may interact with different output modules.
J Mol Microbiol Biotechnol: 2005, 9(2);65-76
[PubMed:16319496]
[WorldCat.org]
[DOI]
(P p)
Original Articles
Additional publications: PubMed
