Difference between revisions of "Smc"
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* '''Structure:''' | * '''Structure:''' | ||
| + | ** [http://www.pdb.org/pdb/explore/explore.do?structureId=3ZGX 3ZGX] (complex between the head domain of [[Smc]] (aa 1 - 219 and 983 - 1186) and the N-terminal winged-helix domain of [[ScpA]]) {{PubMed|23353789}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P51834 P51834] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P51834 P51834] | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=smc_1666560_1670120_1 smc] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=smc_1666560_1670120_1 smc] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|11021934}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|11021934}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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==Original publications== | ==Original publications== | ||
| − | + | '''Additional publications:''' {{PubMed|22385855}} | |
| − | <pubmed>9791128,12100548,17416649,19450516,12421306,11395470, 19450517, 19450516 15009890 16479537 21630458</pubmed> | + | <pubmed>9791128,12100548,17416649,19450516,12421306,11395470, 19450517, 19450516 15009890 16479537 21630458 23353789</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:43, 1 February 2013
- Description: chromosome condensation and segregation SMC protein
| Gene name | smc |
| Synonyms | ylqA |
| Essential | yes PubMed |
| Product | chromosome condensation and segregation SMC protein |
| Function | structural maintenance of the chromosome |
| Gene expression levels in SubtiExpress: smc | |
| Interactions involving this protein in SubtInteract: Smc | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 135 kDa, 5.266 |
| Gene length, protein length | 3558 bp, 1186 aa |
| Immediate neighbours | rnc, ftsY |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
DNA condensation/ segregation, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15940
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SMC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: nucleoid (heterogeneous) PubMed
Database entries
- Structure:
- UniProt: P51834
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Peter L Graumann, Tobias Knust
Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair.
Chromosome Res: 2009, 17(2);265-75
[PubMed:19308706]
[WorldCat.org]
[DOI]
(I p)
Christine Kaimer, Peter L Graumann
Players between the worlds: multifunctional DNA translocases.
Curr Opin Microbiol: 2011, 14(6);719-25
[PubMed:22047950]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
