Difference between revisions of "RatA"
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
| + | ** the ''[[txpA]]'' mRNA-''[[RatA]]'' RNA duplex is degraded by [[rnc|RNase III]] {{PubMed|23300471}} | ||
=Biological materials = | =Biological materials = | ||
Revision as of 14:58, 10 January 2013
| Gene name | ratA |
| Synonyms | |
| Essential | no |
| Product | txpA antisense RNA |
| Function | control of txpA expression |
| Gene length | 222 bp |
| Immediate neighbours | txpA, bsrH |
| Gene sequence (+200bp) | |
| Genetic context File:GenE context.gif | |
Contents
Categories containing this gene/protein
toxins, antitoxins and immunity against toxins, Skin element, ncRNA
This gene is a member of the following regulons
The ratA regulon: txpA
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry:
- Structure:
Additional information
The RNA
binds the txpA mRNA and triggers its degradation PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard University, Cambridge, USA Homepage
Your additional remarks
References
Reviews
Fabian M Commichau, Jörg Stülke
A mystery unraveled: essentiality of RNase III in Bacillus subtilis is caused by resident prophages.
PLoS Genet: 2012, 8(12);e1003199
[PubMed:23300472]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
Jessica M Silvaggi, John B Perkins, Richard Losick
Small untranslated RNA antitoxin in Bacillus subtilis.
J Bacteriol: 2005, 187(19);6641-50
[PubMed:16166525]
[WorldCat.org]
[DOI]
(P p)
