YfmC

• Description: iron/ citrate ABC transporter (binding protein)
  
  

Gene name	yfmC
Synonyms
Essential	no
Product	iron/ citrate ABC transporter (binding protein)
Function	iron uptake
Gene expression levels in SubtiExpress: yfmC
Interactions involving this protein in SubtInteract: YfmC
MW, pI	34 kDa, 7.879
Gene length, protein length	945 bp, 315 aa
Immediate neighbours	yfmD, yfmB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU07520

Phenotypes of a mutant

• poor growth with the Fe(III)-dicitrate as single source of iron PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Fe/B12 periplasmic-binding domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YfmF-(YfmD-YfmE)-(YfmC-YhfQ) PubMed

• Localization:
  • associated to the membrane (via YfmD-YfmE) PubMed
  • extracellular (signal peptide) PubMed, lipid modification as retention signal

Database entries

• Structure:

• UniProt: O34348

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yfmC-yfmD-yfmE-yfmF PubMed

• Expression browser: yfmC PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: