Difference between revisions of "ThyA"
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 837 bp, 279 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 837 bp, 279 aa | ||
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− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ynzJ]]'', ''[[yncM]]'' |
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB13652]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB13652]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
Revision as of 10:14, 3 December 2012
- Description: thymidylate synthase A
Gene name | thyA |
Synonyms | |
Essential | no |
Product | thymidylate synthase A |
Function | biosynthesis of thymidine nucleotides |
Gene expression levels in SubtiExpress: thyA | |
MW, pI | 32 kDa, 5.502 |
Gene length, protein length | 837 bp, 279 aa |
Immediate neighbours | ynzJ, yncM |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU17680
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP (according to Swiss-Prot)
- Protein family: Bacterial-type thyA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1B02
- UniProt: P42326
- KEGG entry: [2]
- E.C. number: 2.1.1.45
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
A Yazgan, G Ozcengiz, M A Marahiel
Tn10 insertional mutations of Bacillus subtilis that block the biosynthesis of bacilysin.
Biochim Biophys Acta: 2001, 1518(1-2);87-94
[PubMed:11267663]
[WorldCat.org]
[DOI]
(P p)