OpuAC

• Description: glycine betaine ABC transporter (binding protein)
  
  

Gene name	opuAC
Synonyms
Essential	no
Product	glycine betaine ABC transporter (binding protein)
Function	compatible solute transport
Gene expression levels in SubtiExpress: opuAC
Interactions involving this protein in SubtInteract: OpuAC
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	32 kDa, 8.015
Gene length, protein length	879 bp, 293 aa
Immediate neighbours	opuAB, amhX
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, coping with hyper-osmotic stress, membrane proteins

The gene

Basic information

• Locus tag: BSU03000

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • OpuAA-OpuAB-OpuAC PubMed

• Localization: associated to the membrane (via OpuAB) PubMed

Database entries

• Structure: 2B4L (complex with glycine betaine), 3CHG (in complex with DMSA)

• UniProt: P46922

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: opuAA-opuAB-opuAC PubMed

• Expression browser: opuAC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by osmotic stress PubMed
  • repressed by intracellular glycine betaine PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage