DtpT

• Description: peptide transporter
  
  

Gene name	yclF
Synonyms	dtpT
Essential	no
Product	peptide transporter
Function	uptake of di- and tripeptides
Gene expression levels in SubtiExpress: yclF
MW, pI	53 kDa, 9.92
Gene length, protein length	1476 bp, 492 aa
Immediate neighbours	yclE, yclG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

ScoC regulon

The gene

Basic information

• Locus tag: BSU03670

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: POT family of secondary (PMF-dependent) transporters

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94408

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yclF PubMed

• Sigma factor:

• Regulation:
  • repressed during exponential growth (ScoC) PubMed

• Regulatory mechanism:
  • ScoC: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

R Caldwell, R Sapolsky, W Weyler, R R Maile, S C Causey, E Ferrari
Correlation between Bacillus subtilis scoC phenotype and gene expression determined using microarrays for transcriptome analysis.
J Bacteriol: 2001, 183(24);7329-40
[PubMed:11717292] [WorldCat.org] [DOI] (P p)

E R Kunji, E J Smid, R Plapp, B Poolman, W N Konings
Di-tripeptides and oligopeptides are taken up via distinct transport mechanisms in Lactococcus lactis.
J Bacteriol: 1993, 175(7);2052-9
[PubMed:8458848] [WorldCat.org] [DOI] (P p)