LytA

• Description: secretion of major autolysin LytC
  
  

Gene name	lytA
Synonyms	lppX
Essential	no
Product	secretion of major autolysin LytC
Function	autolysis
Gene expression levels in SubtiExpress: lytA
MW, pI	11 kDa, 4.061
Gene length, protein length	306 bp, 102 aa
Immediate neighbours	lytB, tagU
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, membrane proteins

This gene is a member of the following regulons

SigD regulon, SlrR regulon, YvrHb regulon

The gene

Basic information

• Locus tag: BSU35640

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q02112

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lytA-lytB-lytC PubMed

• Expression browser: lytA PubMed

• Sigma factor: SigA PubMed, SigD PubMed

• Regulation:

• Regulatory mechanism:
  • SlrR (in complex with SinR: transcription repression PubMed
  • YvrHb: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:
  • 1A789 ( lytA::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: