YxdJ

• Description: two-component response regulator, regulation of the ABC transporter YxdL-YxdM in response to the cationic antimicrobial peptide, LL-37
  
  

Gene name	yxdJ
Synonyms
Essential	no
Product	two-component response regulator
Function	resistance against toxic peptides
Gene expression levels in SubtiExpress: yxdJ
Interactions involving this protein in SubtInteract: YxdJ
MW, pI	26 kDa, 4.937
Gene length, protein length	687 bp, 229 aa
Immediate neighbours	yxdK, iolJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins

The YxdJ regulon:

• yxdL-yxdM-yxeA

The gene

Basic information

• Locus tag: BSU39660

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by YxdK on an Asp residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YxdK-YxdJ

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P42421

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxdJ-yxdK PubMed

• Expression browser: yxdJ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: