YvgJ

• Description: lipoteichoic acid synthesis primase
  
  

Gene name	yvgJ
Synonyms	yvsF
Essential	no
Product	lipoteichoic acid synthesis primase
Function	biosynthesis of lipoteichoic acid
Gene expression levels in SubtiExpress: yvgJ
MW, pI	70 kDa, 5.31
Gene length, protein length	1851 bp, 617 aa
Immediate neighbours	yvsG, yvgK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, membrane proteins

The gene

Basic information

• Locus tag: BSU33360

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LTA synthase family (according to Swiss-Prot)

• Paralogous protein(s): LtaS, YfnI, YqgS

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32206

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yvgJ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Additional reviews: PubMed

Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol Lett: 2011, 319(2);97-105
[PubMed:21388439] [WorldCat.org] [DOI] (I p)

Original publications

Mirka E Wörmann, Rebecca M Corrigan, Peter J Simpson, Steve J Matthews, Angelika Gründling
Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes.
Mol Microbiol: 2011, 79(3);566-83
[PubMed:21255105] [WorldCat.org] [DOI] (I p)

Kathrin Schirner, Jon Marles-Wright, Richard J Lewis, Jeff Errington
Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis.
EMBO J: 2009, 28(7);830-42
[PubMed:19229300] [WorldCat.org] [DOI] (I p)