Difference between revisions of "NadB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || NAD biosynthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || NAD biosynthesis
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27870 nadB]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 58 kDa, 6.445   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 58 kDa, 6.445   

Revision as of 14:26, 7 August 2012

  • Description: L-aspartate oxidase

Gene name nadB
Synonyms
Essential no
Product L-aspartate oxidase
Function NAD biosynthesis
Gene expression levels in SubtiExpress: nadB
MW, pI 58 kDa, 6.445
Gene length, protein length 1593 bp, 531 aa
Immediate neighbours nadC, nifS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NadB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NadB expression.png
























Categories containing this gene/protein

biosynthesis of cofactors, phosphoproteins

This gene is a member of the following regulons

NadR regulon

The gene

Basic information

  • Locus tag: BSU27870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-aspartate + O2 = iminosuccinate + H2O2 (according to Swiss-Prot)
  • Protein family: NadB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-104 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of nicotinic acid (NadR) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage

Your additional remarks

References