Difference between revisions of "FbpB"
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− | + | * '''Description:''' Fur-regulated basic protein, acts as RNA chaperone for ''[[fsrA]]'', response to iron limitation <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || RNA chaperone | |style="background:#ABCDEF;" align="center"|'''Function''' || RNA chaperone | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 9.9 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 9.9 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:FbpA_fbpB_context.jpeg]] | |colspan="2" | '''Genetic context''' <br/> [[Image:FbpA_fbpB_context.jpeg]] | ||
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* '''Operon:''' ''[[fbpA]]-[[fbpB]]'' {{PubMed|18697947}} | * '''Operon:''' ''[[fbpA]]-[[fbpB]]'' {{PubMed|18697947}} | ||
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* '''Regulation:''' | * '''Regulation:''' |
Revision as of 11:30, 7 August 2012
- Description: Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation
Gene name | fbpB |
Synonyms | ydbN |
Essential | no |
Product | Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation |
Function | RNA chaperone |
MW, pI | 6 kDa, 9.9 |
Gene length, protein length | 177 bp, 59 aa |
Immediate neighbours | ydbM, fbpA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context |
Contents
Categories containing this gene/protein
acquisition of iron, iron metabolism, RNA chaperones, short peptides
This gene is a member of the following regulons
The FbpB regulon: lutA-lutB-lutC
The gene
Basic information
- Locus tag: BSU04530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The sequence of the former ydbN gene was corrected, and does now contain two genes, fbpA and fbpB. PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96609
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
- The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Gregory T Smaldone, Haike Antelmann, Ahmed Gaballa, John D Helmann
The FsrA sRNA and FbpB protein mediate the iron-dependent induction of the Bacillus subtilis lutABC iron-sulfur-containing oxidases.
J Bacteriol: 2012, 194(10);2586-93
[PubMed:22427629]
[WorldCat.org]
[DOI]
(I p)
Gregory T Smaldone, Olga Revelles, Ahmed Gaballa, Uwe Sauer, Haike Antelmann, John D Helmann
A global investigation of the Bacillus subtilis iron-sparing response identifies major changes in metabolism.
J Bacteriol: 2012, 194(10);2594-605
[PubMed:22389480]
[WorldCat.org]
[DOI]
(I p)
Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796]
[WorldCat.org]
[DOI]
(I p)
Ahmed Gaballa, Haike Antelmann, Claudio Aguilar, Sukhjit K Khakh, Kyung-Bok Song, Gregory T Smaldone, John D Helmann
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proc Natl Acad Sci U S A: 2008, 105(33);11927-32
[PubMed:18697947]
[WorldCat.org]
[DOI]
(I p)
Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229]
[WorldCat.org]
[DOI]
(P p)