Difference between revisions of "TopB"
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| − | + | * '''Description:''' DNA topoisomerase III <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || replication | |style="background:#ABCDEF;" align="center"|'''Function''' || replication | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 81 kDa, 9.879 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 81 kDa, 9.879 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:topB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:topB_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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* '''Operon:''' | * '''Operon:''' | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
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=Biological materials = | =Biological materials = | ||
Revision as of 11:07, 7 August 2012
- Description: DNA topoisomerase III
| Gene name | topB |
| Synonyms | |
| Essential | no |
| Product | DNA topoisomerase III |
| Function | replication |
| MW, pI | 81 kDa, 9.879 |
| Gene length, protein length | 2181 bp, 727 aa |
| Immediate neighbours | lrpC, ydaJ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
DNA replication, DNA condensation/ segregation
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04260
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP-independent breakage of single-stranded DNA, followed by passage and rejoining (according to Swiss-Prot)
- Protein family: prokaryotic type I/III topoisomerase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96583
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254]
[WorldCat.org]
[DOI]
(P p)
