Difference between revisions of "PurT"
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| − | + | * '''Description:''' phosphoribosylglycinamide formyltransferase 2 <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purine_biosynthesis.html Purine synthesis], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purine_biosynthesis.html Purine synthesis], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:purT_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:purT_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' ''purT'' (according to [http://dbtbs.hgc.jp/COG/prom/purT.html DBTBS]) | * '''Operon:''' ''purT'' (according to [http://dbtbs.hgc.jp/COG/prom/purT.html DBTBS]) | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7496533}} |
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* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 10:45, 7 August 2012
- Description: phosphoribosylglycinamide formyltransferase 2
| Gene name | purT |
| Synonyms | |
| Essential | no |
| Product | phosphoribosylglycinamide formyltransferase 2 |
| Function | purine biosynthesis |
| Metabolic function and regulation of this protein in SubtiPathways: Purine synthesis, Nucleotides (regulation) | |
| MW, pI | 41 kDa, 4.722 |
| Gene length, protein length | 1152 bp, 384 aa |
| Immediate neighbours | ybfI, mpr |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU02230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate (according to Swiss-Prot)
- Protein family: ATP-grasp domain (according to Swiss-Prot)
- Paralogous protein(s): PurK
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P39771
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: purT (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
H H Saxild, J H Jacobsen, P Nygaard
Functional analysis of the Bacillus subtilis purT gene encoding formate-dependent glycinamide ribonucleotide transformylase.
Microbiology (Reading): 1995, 141 ( Pt 9);2211-8
[PubMed:7496533]
[WorldCat.org]
[DOI]
(P p)
