Difference between revisions of "SalA"
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| − | + | * '''Description:''' negative regulator of ''[[scoC]]'' expression <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of alkaline protease expression | |style="background:#ABCDEF;" align="center"|'''Function''' || control of alkaline protease expression | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 38 kDa, 5.23 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 38 kDa, 5.23 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:ybaL_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ybaL_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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* '''Operon:''' | * '''Operon:''' | ||
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* '''Regulation:''' negative autoregulation | * '''Regulation:''' negative autoregulation | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
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=Biological materials = | =Biological materials = | ||
Revision as of 10:35, 7 August 2012
- Description: negative regulator of scoC expression
| Gene name | salA |
| Synonyms | ybaL |
| Essential | no |
| Product | MRP family regulator |
| Function | control of alkaline protease expression |
| MW, pI | 38 kDa, 5.23 |
| Gene length, protein length | 1056 bp, 352 aa |
| Immediate neighbours | cwlD, gerD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transcription factors and their control, transition state regulators
This gene is a member of the following regulons
The SalA regulon:
The gene
Basic information
- Locus tag: BSU01540
Phenotypes of a mutant
increased expression of aprE (due to loss of repression of scoC expression)
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: negative regulation of scoC expression
- Protein family: Mrp/NBP35 ATP-binding proteins family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P50863
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation: negative autoregulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mitsuo Ogura, Atsushi Matsuzawa, Hirofumi Yoshikawa, Teruo Tanaka
Bacillus subtilis SalA (YbaL) negatively regulates expression of scoC, which encodes the repressor for the alkaline exoprotease gene, aprE.
J Bacteriol: 2004, 186(10);3056-64
[PubMed:15126467]
[WorldCat.org]
[DOI]
(P p)
