Difference between revisions of "SecE"

From SubtiWiki
Jump to: navigation, search
m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk)
Line 1: Line 1:
 
+
* '''Description:''' preprotein translocase subunit <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 13: Line 13:
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[protein secretion]]  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[protein secretion]]  
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU01000 secE]
 
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SecE SecE]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SecE SecE]
Line 30: Line 28:
 
|colspan="2" | '''Genetic context''' <br/> [[Image:secE_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:secE_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
 
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=secE_117532_117711_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:secE_expression.png|500px]]
 
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
  
 
<br/><br/>
 
<br/><br/>
Line 118: Line 108:
 
* '''Operon:'''  
 
* '''Operon:'''  
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=secE_117532_117711_1 secE] {{PubMed|22383849}}
+
* '''[[Sigma factor]]:'''  
 
 
* '''Sigma factor:'''  
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 126: Line 114:
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''
+
* '''Additional information:'''  
  
 
=Biological materials =
 
=Biological materials =

Revision as of 09:27, 7 August 2012

  • Description: preprotein translocase subunit

Gene name secE
Synonyms
Essential yes PubMed
Product preprotein translocase subunit
Function protein secretion
Interactions involving this protein in SubtInteract: SecE
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 6 kDa, 10.47
Gene length, protein length 177 bp, 59 aa
Immediate neighbours rpmGB, nusG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SecE context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

protein secretion, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU01000

Phenotypes of a mutant

essential PubMed PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: secE/SEC61-gamma family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: transmembrane protein with a single TM domain
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jochen Zimmer, Yunsun Nam, Tom A Rapoport
Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature: 2008, 455(7215);936-43
[PubMed:18923516] [WorldCat.org] [DOI] (I p)

S M Jeong, H Yoshikawa, H Takahashi
Isolation and characterization of the secE homologue gene of Bacillus subtilis.
Mol Microbiol: 1993, 10(1);133-42
[PubMed:7968510] [WorldCat.org] [DOI] (P p)