Difference between revisions of "RlmCD"
| Line 1: | Line 1: | ||
| − | + | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || 23S rRNA maturation | |style="background:#ABCDEF;" align="center"|'''Function''' || 23S rRNA maturation | ||
| + | |- | ||
| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU06730 rlmCD] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 5.707 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 5.707 | ||
Revision as of 15:43, 6 August 2012
| Gene name | rlmCD |
| Synonyms | yerS, yefA |
| Essential | no |
| Product | rRNA methyltransferase |
| Function | 23S rRNA maturation |
| Gene expression levels in SubtiExpress: rlmCD | |
| MW, pI | 51 kDa, 5.707 |
| Gene length, protein length | 1377 bp, 459 aa |
| Immediate neighbours | dgkB, yefB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06730
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: methylation of U747 and U1939 in 23S rRNA PubMed
- Protein family: COG2265
- Paralogous protein(s): YfjO
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31503
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Benoit Desmolaize, Céline Fabret, Damien Brégeon, Simon Rose, Henri Grosjean, Stephen Douthwaite
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA.
Nucleic Acids Res: 2011, 39(21);9368-75
[PubMed:21824914]
[WorldCat.org]
[DOI]
(I p)
