Difference between revisions of "DgcW"
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| − | * '''Description:''' potential | + | * '''Description:''' potential diguanylate cyclase and phosphodiesterase <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || potential | + | |style="background:#ABCDEF;" align="center"| '''Product''' || potential diguanylate cyclase and phosphodiesterase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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<br/><br/> | <br/><br/> | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' aa 290-735 are similar to ''E. coli'' CsrD (18% identity, 43% similarity) | + | * '''Domains:''' |
| + | ** contains a central GGDEF domain and a C-terminal EAL domain {{PubMed|22821967}} | ||
| + | ** aa 290-735 are similar to ''E. coli'' CsrD (18% identity, 43% similarity) | ||
* '''Modification:''' | * '''Modification:''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' cell membrane (according to Swiss-Prot) | + | * '''[[Localization]]:''' |
| + | ** cell membrane (according to Swiss-Prot) | ||
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | + | '''Additional publications:''' {{PubMed|22821967}} | |
<pubmed>11728710,16980588 , </pubmed> | <pubmed>11728710,16980588 , </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:38, 25 July 2012
- Description: potential diguanylate cyclase and phosphodiesterase
| Gene name | ykoW |
| Synonyms | |
| Essential | no |
| Product | potential diguanylate cyclase and phosphodiesterase |
| Function | unknown |
| MW, pI | 84 kDa, 6.823 |
| Gene length, protein length | 2247 bp, 749 aa |
| Immediate neighbours | ykoV, ykoX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
membrane proteins, metabolism of signalling nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13420
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- contains a central GGDEF domain and a C-terminal EAL domain PubMed
- aa 290-735 are similar to E. coli CsrD (18% identity, 43% similarity)
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O34311
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Kazushi Suzuki, Paul Babitzke, Sidney R Kushner, Tony Romeo
Identification of a novel regulatory protein (CsrD) that targets the global regulatory RNAs CsrB and CsrC for degradation by RNase E.
Genes Dev: 2006, 20(18);2605-17
[PubMed:16980588]
[WorldCat.org]
[DOI]
(P p)
M Y Galperin, T A Gaidenko, A Y Mulkidjanian, M Nakano, C W Price
MHYT, a new integral membrane sensor domain.
FEMS Microbiol Lett: 2001, 205(1);17-23
[PubMed:11728710]
[WorldCat.org]
[DOI]
(P p)
