TatAY

• Description: component of the TatAY-TatCY twin-arginine translocase
  
  

Gene name	tatAY
Synonyms	ydiI
Essential	no
Product	component of the twin-arginine translocation pathway (putative)
Function	TAT protein secretion
Interactions involving this protein in SubtInteract: TatAY
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	5 kDa, 6.558
Gene length, protein length	171 bp, 57 aa
Immediate neighbours	rex, tatCY
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, membrane proteins

The gene

Basic information

• Locus tag: BSU05980

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: secretion of YwbN and of YkuE

• Protein family: tatA/E family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • TatAY-TatCY PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O05522

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: tatAY PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Carmine G Monteferrante, Marcus Miethke, René van der Ploeg, Corinna Glasner, Jan Maarten van Dijl
Specific targeting of the metallophosphoesterase YkuE to the bacillus cell wall requires the twin-arginine translocation system.
J Biol Chem: 2012, 287(35);29789-800
[PubMed:22767609] [WorldCat.org] [DOI] (I p)

René van der Ploeg, James P Barnett, Nishi Vasisht, Vivianne J Goosens, Dierk C Pöther, Colin Robinson, Jan Maarten van Dijl
Salt sensitivity of minimal twin arginine translocases.
J Biol Chem: 2011, 286(51);43759-43770
[PubMed:22041895] [WorldCat.org] [DOI] (I p)

René van der Ploeg, Ulrike Mäder, Georg Homuth, Marc Schaffer, Emma L Denham, Carmine G Monteferrante, Marcus Miethke, Mohamed A Marahiel, Colin R Harwood, Theresa Winter, Michael Hecker, Haike Antelmann, Jan Maarten van Dijl
Environmental salinity determines the specificity and need for Tat-dependent secretion of the YwbN protein in Bacillus subtilis.
PLoS One: 2011, 6(3);e18140
[PubMed:21479178] [WorldCat.org] [DOI] (I e)

Robyn T Eijlander, Magdalena A Kolbusz, Erwin M Berendsen, Oscar P Kuipers
Effects of altered TatC proteins on protein secretion efficiency via the twin-arginine translocation pathway of Bacillus subtilis.
Microbiology (Reading): 2009, 155(Pt 6);1776-1785
[PubMed:19383693] [WorldCat.org] [DOI] (P p)

Jan D H Jongbloed, Ulrike Grieger, Haike Antelmann, Michael Hecker, Reindert Nijland, Sierd Bron, Jan Maarten van Dijl
Two minimal Tat translocases in Bacillus.
Mol Microbiol: 2004, 54(5);1319-25
[PubMed:15554971] [WorldCat.org] [DOI] (P p)