LytH

• Description: differentiation-associated peptidoglycan hydrolase involved in endospore cortex maturation
  
  

Gene name	lytH
Synonyms	yunA, yutA
Essential	no
Product	peptidoglycan hydrolase
Function	endospore cortex maturation
MW, pI	39 kDa, 6.893
Gene length, protein length	1047 bp, 349 aa
Immediate neighbours	lipA, yunB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall/ other, sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU32340

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M23B family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O32130

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: lytH PubMed

• Expression browser: lytH PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Gavin J Horsburgh, Abdelmadjid Atrih, Simon J Foster
Characterization of LytH, a differentiation-associated peptidoglycan hydrolase of Bacillus subtilis involved in endospore cortex maturation.
J Bacteriol: 2003, 185(13);3813-20
[PubMed:12813075] [WorldCat.org] [DOI] (P p)