Difference between revisions of "ComP"
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* '''Operon:''' ''comP'' {{PubMed|9274030}} | * '''Operon:''' ''comP'' {{PubMed|9274030}} | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comP_3253529_3255838_-1 comP] {{PubMed|22383849}} |
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+ | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 16:26, 16 April 2012
- Description: two-component sensor kinase, detects extracellular ComX
Gene name | comP |
Synonyms | |
Essential | no |
Product | two-component sensor kinase |
Function | regulation of genetic competence and quorum sensing |
Interactions involving this protein in SubtInteract: ComP | |
MW, pI | 89 kDa, 7.997 |
Gene length, protein length | 2307 bp, 769 aa |
Immediate neighbours | comA, comX |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
genetic competence, protein modification, transcription factors and their control, quorum sensing, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of ComA
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: eight transmembrane segments
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity: ComX (extracellular)
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: Q99027
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: comP PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Leendert W Hamoen, Gerard Venema, Oscar P Kuipers
Controlling competence in Bacillus subtilis: shared use of regulators.
Microbiology (Reading): 2003, 149(Pt 1);9-17
[PubMed:12576575]
[WorldCat.org]
[DOI]
(P p)
Original Publications