Difference between revisions of "Gmk"
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Revision as of 08:42, 13 April 2012
- Description: guanylate kinase (GMP:dATP, dGMP:ATP)
| Gene name | gmk |
| Synonyms | yloD |
| Essential | yes PubMed |
| Product | guanylate kinase (GMP:dATP, dGMP:ATP) |
| Function | GTP biosynthesis |
| Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation) | |
| MW, pI | 23 kDa, 4.616 |
| Gene length, protein length | 612 bp, 204 aa |
| Immediate neighbours | ylzA, yloH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15680
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + GMP = ADP + GDP (according to Swiss-Prot)
- Protein family: guanylate kinase-like domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1S4Q (from Mycobacterium tuberculosis h37rv, 39% identity, 60% similarity)
- UniProt: O34328
- KEGG entry: [2]
- E.C. number: 2.7.4.8
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
