Difference between revisions of "SbcC"
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* '''Operon:''' ''[[sbcD]]-[[sbcC]]-[[yisB]]'' (according to [http://dbtbs.hgc.jp/COG/prom/sbcD-yirY-yisB.html DBTBS]) | * '''Operon:''' ''[[sbcD]]-[[sbcC]]-[[yisB]]'' (according to [http://dbtbs.hgc.jp/COG/prom/sbcD-yirY-yisB.html DBTBS]) | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sbcC_1144749_1148141_1 sbcC] {{PubMed|22383849}} |
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| + | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 17:25, 12 April 2012
- Description: DNA exonuclease
| Gene name | sbcC |
| Synonyms | yirY |
| Essential | no |
| Product | DNA exonuclease |
| Function | DNA inter-strand cross-link repair |
| Interactions involving this protein in SubtInteract: SbcC | |
| MW, pI | 128 kDa, 5.294 |
| Gene length, protein length | 3390 bp, 1130 aa |
| Immediate neighbours | sbcD, yisB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
DNA repair/ recombination, genetic competence
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10650
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SbcC subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: Nucleoid (Mid-cell) PubMed
Database entries
- Structure:
- UniProt: O06714
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- GP894 (sbcCD::kan), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Graumann, Freiburg University, Germany homepage
Your additional remarks
References
Reviews
Original publications
Judita Mascarenhas, Humberto Sanchez, Serkalem Tadesse, Dawit Kidane, Mahalakshmi Krisnamurthy, Juan C Alonso, Peter L Graumann
Bacillus subtilis SbcC protein plays an important role in DNA inter-strand cross-link repair.
BMC Mol Biol: 2006, 7;20
[PubMed:16780573]
[WorldCat.org]
[DOI]
(I e)
Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Hirotake Yamaguchi, Kazuo Kobayashi, Naotake Ogasawara, Yasutaro Fujita, Teruo Tanaka
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK.
J Bacteriol: 2002, 184(9);2344-51
[PubMed:11948146]
[WorldCat.org]
[DOI]
(P p)
Additional publications: PubMed
