Difference between revisions of "CssS"

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(Extended information on the protein)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
 +
** the extracellular loop domain is required for signal perception {{PubMed|22307758}}
  
 
* '''[[SubtInteract|Interactions]]:'''  
 
* '''[[SubtInteract|Interactions]]:'''  
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** [[CssS]]-[[CssR]]
 
** [[CssS]]-[[CssR]]
  
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
+
* '''[[Localization]]:'''  
 +
** cell membrane (according to Swiss-Prot)
 +
** localized primarily at the division septum but also found in a punctate pattern with lower intensity throughout the cell cylinder  {{PubMed|22307758}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
  
<pubmed>10094672,17600057,21630458,17088376,12270824,11555295, 19820159 21602801 21624103</pubmed>
+
<pubmed>10094672,17600057,21630458,17088376,12270824,11555295, 19820159 21602801 21624103 22307758</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:28, 13 February 2012

  • Description: two-component sensor kinase, control of cellular responses to protein secretion stress

Gene name cssS
Synonyms yvqB
Essential no
Product two-component sensor kinase
Function control of cellular responses to protein secretion stress
Interactions involving this protein in SubtInteract: CssS
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 51 kDa, 5.795
Gene length, protein length 1353 bp, 451 aa
Immediate neighbours cssR, yirB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CssS context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

protein modification, transcription factors and their control, heat shock proteins, membrane proteins, phosphoproteins

This gene is a member of the following regulons

CssR regulon

The gene

Basic information

  • Locus tag: BSU33020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of CssR
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
    • the extracellular loop domain is required for signal perception PubMed
  • Localization:
    • cell membrane (according to Swiss-Prot)
    • localized primarily at the division septum but also found in a punctate pattern with lower intensity throughout the cell cylinder PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of secretion stress (CssR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References