KamA

• Description: lysine 2,3-aminomutase
  
  

Gene name	kamA
Synonyms	yodO
Essential	no
Product	lysine 2,3-aminomutase
Function	unknown
MW, pI	53 kDa, 6.04
Gene length, protein length	1413 bp, 471 aa
Immediate neighbours	yokU, yodP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU19690

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-lysine = beta-lysine

• Protein family: UPF0720 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34676

• KEGG entry: [2]

• E.C. number: 5.4.3.2

Expression and regulation

• Operon: yodT-yodS-yodR-yodQ-yodP-kamA-yokU PubMed

• Sigma factor: SigE PubMed

• Regulation: expressed early during sporuation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133] [WorldCat.org] [DOI] (P p)

D Chen, F J Ruzicka, P A Frey
A novel lysine 2,3-aminomutase encoded by the yodO gene of bacillus subtilis: characterization and the observation of organic radical intermediates.
Biochem J: 2000, 348 Pt 3(Pt 3);539-49
[PubMed:10839984] [WorldCat.org] (P p)