SodF

• Description: superoxide dismutase
  
  

Gene name	sodF
Synonyms
Essential	no
Product	superoxide dismutase
Function	detoxification of oxygen radicals
MW, pI	33 kDa, 6.17
Gene length, protein length	843 bp, 281 aa
Immediate neighbours	sqhC, yocR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU19330

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2 superoxide + 2 H⁺ = O₂ + H₂O₂ (according to Swiss-Prot)

• Protein family: terpene cyclase/mutase family (according to Swiss-Prot)

• Paralogous protein(s): SodA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O35023

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: sqhC-sodF PubMed

• Sigma factor: SigE PubMed

• Regulation: expressed during sporulation in the mother cell PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

T Bosak, R M Losick, A Pearson
A polycyclic terpenoid that alleviates oxidative stress.
Proc Natl Acad Sci U S A: 2008, 105(18);6725-9
[PubMed:18436644] [WorldCat.org] [DOI] (I p)