Difference between revisions of "MhqR"
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| − | * '''Description:''' MarR-family transcriptional repressor of | + | * '''Description:''' MarR-family transcriptional repressor of azoR2, mhqA, mhqDE and mhqNOP expression <br/><br/> |
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=The [[MhqR regulon]]= | =The [[MhqR regulon]]= | ||
| − | * | + | * azoR2, mhqA, mhqDE and mhqNOP |
=The gene= | =The gene= | ||
Revision as of 15:57, 15 December 2011
- Description: MarR-family transcriptional repressor of azoR2, mhqA, mhqDE and mhqNOP expression
| Gene name | mhqR |
| Synonyms | ykvE |
| Essential | no |
| Product | MarR-family transcriptional repressor |
| Function | regulation of resistance to quinones and diamide |
| MW, pI | 16 kDa, 6.42 |
| Gene length, protein length | 435 bp, 145 aa |
| Immediate neighbours | kinD, motB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The MhqR regulon
- azoR2, mhqA, mhqDE and mhqNOP
The gene
Basic information
- Locus tag: BSU13670
Phenotypes of a mutant
- resistant to quinones and diamide
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31672
- KEGG entry: [2]
- E.C. number:
Additional information
- Binding site: tATCTcgaAtTCgAGATaaaa PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564]
[WorldCat.org]
[DOI]
(P p)
