Difference between revisions of "MinD"

From SubtiWiki
Jump to: navigation, search
(Extended information on the protein)
Line 83: Line 83:
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' ([[MinC]]-[[MinD]])-[[MinJ]]-[[DivIVA]] {{PubMed|20352045}}
+
* '''[[SubtInteract|Interactions]]:'''
 +
** ([[MinC]]-[[MinD]])-[[MinJ]]-[[DivIVA]] {{PubMed|20352045}}
  
* '''Localization:'''  
+
* '''[[Localization]]:'''  
 
** polar/ septal at the cell membrane {{PubMed|20566861}}  
 
** polar/ septal at the cell membrane {{PubMed|20566861}}  
 
** membrane binding/ polar localization depends on the proton motive force {{PubMed|20566861}}
 
** membrane binding/ polar localization depends on the proton motive force {{PubMed|20566861}}

Revision as of 12:34, 10 August 2011

  • Description: cell-division inhibitor (septum placement)

Gene name minD
Synonyms divIVB1
Essential no
Product cell-division inhibitor
Function septum placement
Interactions involving this protein in SubtInteract: MinD
MW, pI 29 kDa, 4.984
Gene length, protein length 804 bp, 268 aa
Immediate neighbours spoIVFA, minC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MinD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell division, cell envelope stress proteins (controlled by SigM, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigH regulon, SigM regulon

The gene

Basic information

  • Locus tag: BSU27990

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle PubMed
  • Protein family: MinD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • polar/ septal at the cell membrane PubMed
    • membrane binding/ polar localization depends on the proton motive force PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039] [WorldCat.org] [DOI] (I p)

Original Publications