Difference between revisions of "RlmCD"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' rRNA methyltransferase <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''rlmCD'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yerS '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yerS, yefA '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || rRNA methyltransferase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || 23S rRNA maturation |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 5.707 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 5.707 | ||
| Line 60: | Line 60: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' methylation of U747 and U1939 in 23S rRNA {{PubMed|21824914}} |
| − | + | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' COG2265 |
* '''Paralogous protein(s):''' [[YfjO]] | * '''Paralogous protein(s):''' [[YfjO]] | ||
| Line 125: | Line 125: | ||
=References= | =References= | ||
| − | + | <pubmed>21824914</pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 07:32, 10 August 2011
- Description: rRNA methyltransferase
| Gene name | rlmCD |
| Synonyms | yerS, yefA |
| Essential | no |
| Product | rRNA methyltransferase |
| Function | 23S rRNA maturation |
| MW, pI | 51 kDa, 5.707 |
| Gene length, protein length | 1377 bp, 459 aa |
| Immediate neighbours | dgkB, yefB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06730
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: methylation of U747 and U1939 in 23S rRNA PubMed
- Protein family: COG2265
- Paralogous protein(s): YfjO
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O31503
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Benoit Desmolaize, Céline Fabret, Damien Brégeon, Simon Rose, Henri Grosjean, Stephen Douthwaite
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA.
Nucleic Acids Res: 2011, 39(21);9368-75
[PubMed:21824914]
[WorldCat.org]
[DOI]
(I p)
