Difference between revisions of "Universally conserved proteins"
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[[ArgS]], [[PheS]], [[GltX]] | [[ArgS]], [[PheS]], [[GltX]] | ||
− | ==Degradation of glycoproteins== | + | ==Degradation of glycoproteins and/or tRNA modification== |
* [[Gcp]] sialo-glycoprotein endopeptidase | * [[Gcp]] sialo-glycoprotein endopeptidase | ||
==Note== | ==Note== | ||
[[FtsZ]] has long been considered to be universally conserved. However, recently some ''Mycoplasma'' species lacking [[FtsZ]] have been found. | [[FtsZ]] has long been considered to be universally conserved. However, recently some ''Mycoplasma'' species lacking [[FtsZ]] have been found. | ||
+ | |||
+ | ==Important publications== | ||
+ | <pubmed> 15479782 </pubmed> | ||
+ | |||
=Back to [[categories]]= | =Back to [[categories]]= |
Revision as of 13:01, 1 August 2011
These proteins are present in all genomes sequenced so far, from archaea and bacteria to man. So, one can say, that there is no life on earth without this small set of proteins. The genes encoding these proteins are usually essential.
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Contents
Glycolytic enzymes
Ribosomal proteins
RplA, RplB, RplC, RplE, RplF, RplK, RplN, RplR, RplV, RpsB, RpsC, RpsD, RpsE, RpsG, RpsH, RpsJ, RpsM, RpsQ, RpsS
Cellular processes
Nucleotide metabolism
- Prs phosphoribosyl-PP-synthetase
- Apt adenine phosphoribosyltransferase
- TruA pseudouridylate synthase
Aminoacyl tRNA synthetases
Degradation of glycoproteins and/or tRNA modification
- Gcp sialo-glycoprotein endopeptidase
Note
FtsZ has long been considered to be universally conserved. However, recently some Mycoplasma species lacking FtsZ have been found.
Important publications
Michael Y Galperin, Eugene V Koonin
'Conserved hypothetical' proteins: prioritization of targets for experimental study.
Nucleic Acids Res: 2004, 32(18);5452-63
[PubMed:15479782]
[WorldCat.org]
[DOI]
(I e)