Localization

The proteins of B. subtilis can be localized in different parts of the cell and they can be secreted. Several studies have a focus on protein localization.

• Important localizations in the vegetative cell:
  • cytoplasm
  • membrane
  • cell wall
  • secreted

• Important localizations in the spore:
  • cytoplasm
  • membrane
  • spore cortex

Important publications

Andreas Otto, Jörg Bernhardt, Hanna Meyer, Marc Schaffer, Florian-A Herbst, Juliane Siebourg, Ulrike Mäder, Michael Lalk, Michael Hecker, Dörte Becher
Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis.
Nat Commun: 2010, 1;137
[PubMed:21266987] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Annette Dreisbach, Andreas Otto, Dörte Becher, Elke Hammer, Alexander Teumer, Joost W Gouw, Michael Hecker, Uwe Völker
Monitoring of changes in the membrane proteome during stationary phase adaptation of Bacillus subtilis using in vivo labeling techniques.
Proteomics: 2008, 8(10);2062-76
[PubMed:18491319] [WorldCat.org] [DOI] (I p)

Geeske Zanen, Haike Antelmann, Rob Meima, Jan D H Jongbloed, Marc Kolkman, Michael Hecker, Jan Maarten van Dijl, Wim J Quax
Proteomic dissection of potential signal recognition particle dependence in protein secretion by Bacillus subtilis.
Proteomics: 2006, 6(12);3636-48
[PubMed:16705751] [WorldCat.org] [DOI] (P p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Harold Tjalsma, Haike Antelmann, Jan D H Jongbloed, Peter G Braun, Elise Darmon, Ronald Dorenbos, Jean-Yves F Dubois, Helga Westers, Geeske Zanen, Wim J Quax, Oscar P Kuipers, Sierd Bron, Michael Hecker, Jan Maarten van Dijl
Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome.
Microbiol Mol Biol Rev: 2004, 68(2);207-33
[PubMed:15187182] [WorldCat.org] [DOI] (P p)